Freeze-Thaw Cycles Enhance Decellularization of Large Tendons
نویسندگان
چکیده
منابع مشابه
Automated freeze-thaw cycles for decellularization of tendon tissue - a pilot study
BACKGROUND Decellularization of tendon tissue plays a pivotal role in current tissue engineering approaches for in vitro research as well as for translation of graft-based tendon restoration into clinics. Automation of essential decellularization steps like freeze-thawing is crucial for the development of more standardized decellularization protocols and commercial graft production under good m...
متن کاملSimulating Martian Conditions: Methanogen Survivability during Freeze-thaw Cycles
Introduction: Methanogens are obligate anaerobes that use molecular hydrogen as an energy source and carbon dioxide as a carbon source to produce methane. They are classified as Archaea and are found in many extreme environments, including hydrothermal vents, volcanoes, and also the human microflora. The current Martian atmosphere is low in pressure, very dry (hyper-arid), and high in radiation...
متن کاملStrength Characteristics of Clay Mixtures with Waste Materials in Freeze-Thaw Cycles
Waste tires, rubbers, plastic and steel materials, normally produced in every society, enter the environment and cause serious problems. These problems may, to some extent, be reduced by finding applications for them in engineering, for example, they can be used for geotechnical applications as backfill material and solving problems with low shear strength soils. Such materials may be subjected...
متن کاملFreeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model
OBJECTIVE The trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might be a viable therapeutic approach. Decellularized TM scaffolds have previously been produced by ablating cells with suicide gene therapy or saponin, which risks incomplete cell removal or dissolution of the extracellular matrix...
متن کاملFreeze-Thaw Bayesian Optimization
In machine learning, the term “training” is used to describe the procedure of fitting a model to data. In many popular models, this fitting procedure is framed as an optimization problem, in which a loss is minimized as a function of the parameters. In all but the simplest machine learning models, this minimization must be performed with an iterative algorithm such as stochastic gradient descen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tissue Engineering Part C: Methods
سال: 2014
ISSN: 1937-3384,1937-3392
DOI: 10.1089/ten.tec.2012.0760